Tuesday, September 18, 2012

Anomaly

a·nom·a·ly  (-nm-l)n. pl. a·nom·a·lies
1. Deviation or departure from the normal or common order, form, or rule.
2. One that is peculiar, irregular, abnormal, or difficult to classify
3. Weston Wyatt Golden


After the re-review of his biopsy, the conclusion is Chronic Rejection.
 Probably. 
Most likely.
Surely?

I know what you are wondering...HOW can he be "chronically rejecting" when he's never rejected before?
Ah. That's the good part.
Evidently, he HAS been in rejection for quite some time, yet his liver panel never showed such evidence.
What?
Yep.
Is that possible?
Evidently it is now.
This doctor has only seen this sleeper chronic rejection in ONE other kid.

Of course there still is the off chance that he's in Acute rejection coupled with something weird and bizaaro, like the antibiotic thing.
Probably not, though, as he hasn't taken amoxil in over a week and his GGT continues to rise.

My diagram of what is wrong with Bubby.

What now?
Imuran.
Ugh.
Imuran is another immunosuppresant that works on another aspect of the immune system.
So, he's on Prograf and that is working at keeping most of his immune system from attacking the transplanted liver. But those bastard bile ducts have to so darn tempting.
The goal of the second immunosuppressant is to further "blind" his immune system so it can't see those bile ducts.
At least that's the way I understand it.
He did say that his liver tissue looked really good and had hardly any fibrosis or cirrhosis.
That is awesome news!
I have tried very hard to wheedle out of them a long term prognosis on this Chronic business.
To say they are not forthcoming, is an understatement.
What I gather is:
If they can get the disappearing bile duct act under control (with the added Imuran), he has a chance of letting them regenerate and he'll be just fine with the liver he has.
If they can't get it under control and they keep disappearing...we're in trouble.
What do you mean "trouble"?
Hey! Look at that bird!

Ok, maybe not that bad, but definitely not super clear.

Imuran starts tomorrow. Of course, they need to monitor him on that for a few days, to make sure he doesn't have a reaction (ie nuetropenia) and they get the dosing right.
MAYBE.
M.A.Y.B.E.
We can go home in a few days.

PS:
Victory is MINE!!
Even if it is at 0700 am SHARP!


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